新冠疫苗簡介
英國皇家婦產科學院
Q. 如果我正在哺餵母乳,我可以接種COVID-19疫苗嗎?
2020年12月30日發布的JCVI建議說,給哺乳期婦女接種現有的COVID-19疫苗沒有已知的風險。
哺乳期婦女在符合條件時將提供疫苗接種。
儘管缺乏這些特定疫苗在母乳哺餵中的安全數據,但沒有任何合理的機制可以讓任何疫苗成分通過母乳傳給你的寶寶。因此,您不應該為了接種COVID-19疫苗而停止母乳。
原文與資料來源
Q. Can I have a COVID-19 vaccine if I am breastfeeding?
The JCVI advice published on 30 December 2020 says there is no known risk in giving available COVID-19 vaccines to breastfeeding women.
Breastfeeding women will now be offered vaccination at the time when they become eligible.
Although there is lack of safety data for these specific vaccines in breastfeeding, there is no plausible mechanism by which any vaccine ingredient could pass to your baby through breast milk. You should therefore not stop breastfeeding in order to be vaccinated against COVID-19.
接種疫苗後 6 週,母乳中會大量分泌 SARS-CoV-2 特異性 IgA 和 IgG 抗體。 (用以保護幼兒)
原文與資料來源
This study found robust secretion of SARS-CoV-2 specific IgA and IgG antibodies in breast milk for 6 weeks after vaccination
資料來源 : https://jamanetwork.com/journals/jama/fullarticle/2778766
Moderna mRNA vaccine 有使用 tromethamine or trometamol 為賦形劑 (excipient) ,這也是許多含碘造影劑或含釓MRI 造影劑常用的賦形劑。因此若病人曾對造影劑過敏,施打 Moderna 疫苗有可能增加過敏風險。
原文與資料來源
Previous histories of allergic reactions, including drugs and contrast media, were described in most of the patients (90%), with previous anaphylaxis episodes in 5 out of 9 patients, including anaphylaxis to contrast media in two patients.8
https://www.sciencedirect.com/science/article/pii/S1323893021000459
美國 CDC 分析過打 Moderna vaccine 產生 anaphylaxis 的十位病患,其中兩位可追蹤到對造影劑過敏 (連結網頁 table)
目前台灣有在使用含有該成分的顯影劑:
CT contrast:
Iopamidol (Iopamiro)
Iodixanol (Visipaque)
Iopamidol (Isovue)
Iohexol (Omnipaque)
Iobitridol (Xenetix)
Ioversol (Optiray)
Iopromide (Ultravist)
MR contrast:
Gadobutrol (Gadovist)
https://www.cdc.gov/mmwr/volumes/70/wr/mm7002e1.htm
延伸閱讀 :
孕婦、哺乳期到底可不可以打COVID-19疫苗? https://www.facebook.com/guanyingh/posts/10159713141764551
新冠肺炎疫苗釋疑
https://www.youtube.com/watch?v=mv_QDb8llXs
COVID-19 疫苗 知識就是力量 ( by NTUH FM VS張皓翔,R郭亭亞,R吳璨宇 )
https://docs.google.com/document/d/17iDs9SuiUZSSOkc74QcFjmUhHvb1pW3oBcXZ--iQJSM/preview